Casis or Casís is a surname. Notable people with this name include:
Ana Casís, Panamanian sociologist, statistician, and demographer
Jazminne Casis, Australian gymnast in 2012 Pacific Rim Gymnastics Championships – Women's Artistic Gymnastics
Julio Súmar Casis (born 1931), Peruvian chess player
Luis Casis, Panamanian politician, vice-presidential candidate in 2019 Panamanian general election
Tomasa Ester Casís (1878–1962), Panamanian teacher and women's rights activist