Seina may refer to:
Seina (kickboxer) (聖愛, born 2001), Japanese professional kickboxer
Seina Nakajima (中嶋 星奈, born 1997), Japanese curler
Seina Saito (齋藤 聖奈, born 1992), Japanese rugby union and rugby sevens player
Seina Shimabukuro (島袋 聖南, born 1987), Japanese model and reality television contestant
