Chimezie is both a given name and a surname. Notable people with the name include:
Chimezie Ikeazor (1930–2012), Nigerian lawyer
Chimezie Imo, Nigerian actor
Chimezie Mbah (born 1992), Nigerian footballer
Chimezie Metu (born 1997), Nigerian-American basketball player
Chimezie Onwuzulike (born 1987), Nigerian cricketer
Bright Chimezie (born 1960), Nigerian musician
Maxwell Chimezie Egwuatu (born 1991), Nigerian footballer
