Helio may refer to:
Helio AU-24 Stallion
Helio (wireless carrier), a defunct American wireless communications provider (2005–2010); originally a joint venture between SK Telecom and EarthLink, purchased by Virgin Mobile USA in 2008
Helio (Cambridge Glass), a short-lived glassware range
Helio Aircraft Company, an aircraft manufacturing company
Helio Courier, a light C/STOL utility aircraft designed in 1949