Putumayo may refer to:
Putumayo Department, Colombia
Putumayo Province, Loreto Region, Peru
Putumayo District, Putumayo Province, Loreto Region, Peru
Putumayo Canton, Ecuador
Putumayo River or Içá River, a river in South America
Putumayo World Music, a record label
Putumayo, a fictional store in the Seinfeld episode "The Millennium"
