Ștefănescu is a common family name in Romania. Persons named Ștefănescu include:
Andrei Ștefănescu, musician
Barbu Ștefănescu Delavrancea, writer
Cornelia Ștefănescu, literary critic and historian
Costică Ștefănescu, footballer
Eugeniu Ștefănescu-Est, writer
Eusebiu Ștefănescu, actor
Florian Ștefănescu-Goangă, psychologist
George Ștefănescu, painter
Grigoriu Ștefănescu, geologist
Melchisedec Ștefănescu, bishop and historian
Sabba S. Ștefănescu, geophysicist
Ștefan Ștefănescu, historian