Amoss is a surname. Notable people with the surname include:
David Amoss, American tobacco farmer
Jim Amoss (born 1947), American journalist, former editor of The Times-Picayune
Thomas M. Amoss (born 1961), American thoroughbred horse trainer
Ulius Louis Amoss (1895–1961), American intelligence officer
William H. Amoss (1936–1997), American politician
