Mathilde is an alternative spelling of the names Matilde or Matilda, and could refer to:
Mathilde Dolgopol de Sáez (1901 –1957), Argentinian vertebrate paleontologist
Mathilde, Abbess of Essen (949–1011)
Mathilde Alanic (1864-1948), French novelist, short story writer
Mathilde Bonaparte (1820-1904), French princess and salonnière
Matilde Camus (1919–2012), Spanish poet
Mathilde Esch (1815–1904), Austrian genre painter
Mathilde Hupin (born 1984), Canadian orthopaedic surgeon and cyclist
Mathilde Kschessinska (1872–1971), ballet dancer
Mathilde Wildauer (1820–1878), actress and opera singer
Queen Mathilde of Belgium (born 1973)
Mathilde Wolff Van Sandau (1843–1926), British suffragette
253 Mathilde, an asteroid
Mathilde (film), a 2004 film
"Mathilde" (song), by Jacques Brel, 1964
Matilde di Shabran, an opera by Gioachino Rossini
Schipper naast Mathilde, a 1950s Flemish TV series
